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Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome

Macrophages reprogram their lipid metabolism in response to activation signals. However, a systems-level understanding of how different pro-inflammatory stimuli reshape the macrophage lipidome is lacking. Here, we use complementary “shotgun” and isotope tracer mass spectrometry approaches to define...

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Bibliographic Details
Published in:Cell Metab
Main Authors: Hsieh, Wei-Yuan, Zhou, Quan D., York, Autumn G., Williams, Kevin J., Scumpia, Philip O., Kronenberger, Eliza B., Hoi, Xen Ping, Su, Baolong, Chi, Xun, Bui, Viet L., Khialeeva, Elvira, Kaplan, Amber, Son, Young Min, Divakaruni, Ajit S., Sun, Jie, Smale, Stephen T., Flavell, Richard A., Bensinger, Steven J.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891175/
https://ncbi.nlm.nih.gov/pubmed/32516576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.05.003
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