Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins

Plasma membranes of animal cells are enriched for cholesterol. Cholesterol-dependent cytolysins (CDCs) are pore forming toxins secreted by bacteria that target membrane cholesterol for their effector function. Phagocytes are essential for clearance of CDC-producing bacteria; however, mechanisms thes...

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Detaylı Bibliyografya
Yayımlandı:Nat Immunol
Asıl Yazarlar: Zhou, Quan D., Chi, Xun, Lee, Min Sub, Hsieh, Wei Yuan, Mkrtchyan, Jonathan J., Feng, An-Chieh, He, Cuiwen, York, Autumn G, Bui, Viet L., Kronenberger, Eliza B., Ferrari, Alessandra, Xiao, Xu, Daly, Allison E., Tarling, Elizabeth J., Damoiseaux, Robert, Scumpia, Philip O., Smale, Stephen T., Williams, Kevin J., Tontonoz, Peter, Bensinger, Steven J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778040/
https://ncbi.nlm.nih.gov/pubmed/32514064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0695-4
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