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FiNGS: high quality somatic mutations using filters for next generation sequencing

BACKGROUND: Somatic variant callers are used to find mutations in sequencing data from cancer samples. They are very sensitive and have high recall, but also may produce low precision data with a large proportion of false positives. Further ad hoc filtering is commonly performed after variant callin...

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Pubblicato in:BMC Bioinformatics
Autori principali: Wardell, Christopher Paul, Ashby, Cody, Bauer, Michael Anton
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7890800/
https://ncbi.nlm.nih.gov/pubmed/33602113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-03995-y
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