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Metformin Attenuates Renal Fibrosis in a Mouse Model of Adenine-Induced Renal Injury Through Inhibiting TGF-β1 Signaling Pathways

It is well-known that all progressive chronic kidney disease (CKD) is pathologically characterized by tubulointerstitial fibrosis process. Multiple studies have shown the critical role of inflammation and fibrosis in the development of CKD. Hence strategies that target inflammatory and fibrotic sign...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Yi, Hao, Huang, Chunling, Shi, Ying, Cao, Qinghua, Chen, Jason, Chen, Xin-Ming, Pollock, Carol A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889967/
https://ncbi.nlm.nih.gov/pubmed/33614642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.603802
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