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RIPK3 blockade attenuates tubulointerstitial fibrosis in a mouse model of diabetic nephropathy
Receptor-interacting protein kinase-3 (RIPK3) is a multifunctional regulator of cell death and inflammation. RIPK3 controls cellular signalling through the formation of the domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome, which is recognised to mediate renal fibrogenesis....
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7319952/ https://ncbi.nlm.nih.gov/pubmed/32591618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67054-x |
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