Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections

BACKGROUND: Thresholds for SARS-CoV-2 antibody assays have typically been determined using samples from symptomatic, often hospitalised, patients. In this setting the sensitivity and specificity of the best performing assays can both exceed 98%. However, antibody assay performance following mild inf...

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Dades bibliogràfiques
Publicat a:BMC Infect Dis
Autors principals: Eyre, David W., Lumley, Sheila F., O’Donnell, Denise, Stoesser, Nicole E., Matthews, Philippa C., Howarth, Alison, Hatch, Stephanie B., Marsden, Brian D., Cox, Stuart, James, Tim, Cornall, Richard J., Stuart, David I., Screaton, Gavin, Ebner, Daniel, Crook, Derrick W., Conlon, Christopher P., Jeffery, Katie, Walker, Timothy M., Peto, Timothy E. A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889711/
https://ncbi.nlm.nih.gov/pubmed/33602152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-021-05878-2
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