Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections

BACKGROUND: Thresholds for SARS-CoV-2 antibody assays have typically been determined using samples from symptomatic, often hospitalised, patients. In this setting the sensitivity and specificity of the best performing assays can both exceed 98%. However, antibody assay performance following mild inf...

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Detaylı Bibliyografya
Yayımlandı:BMC Infect Dis
Asıl Yazarlar: Eyre, David W., Lumley, Sheila F., O’Donnell, Denise, Stoesser, Nicole E., Matthews, Philippa C., Howarth, Alison, Hatch, Stephanie B., Marsden, Brian D., Cox, Stuart, James, Tim, Cornall, Richard J., Stuart, David I., Screaton, Gavin, Ebner, Daniel, Crook, Derrick W., Conlon, Christopher P., Jeffery, Katie, Walker, Timothy M., Peto, Timothy E. A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889711/
https://ncbi.nlm.nih.gov/pubmed/33602152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-021-05878-2
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