Neoadjuvant chemotherapy alters the balance of effector to suppressor immune cells in advanced ovarian cancer

BACKGROUND: At diagnosis, tumor-infiltrating lymphocytes (TILs) are prognostic in epithelial ovarian cancer (EOC). We recently demonstrated that neoadjuvant chemotherapy (NACT) significantly increased stromal TILs. Here, we investigated the impact of NACT on immune subpopulations with a particular f...

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Bibliographic Details
Published in:Cancer Immunol Immunother
Main Authors: Leary, Alexandra, Genestie, Catherine, Blanc-Durand, Félix, Gouy, Sébastien, Dunant, Ariane, Maulard, Amandine, Drusch, Françoise, Cheaib, Bianca, Michels, Judith, Bentivegna, Enrica, LeFormal, Audrey, Mesnage, Soizick, Morice, Philippe, Pautier, Patricia, Khairallah, Aya S.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889679/
https://ncbi.nlm.nih.gov/pubmed/32852603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02670-0
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