Neoadjuvant chemotherapy alters the balance of effector to suppressor immune cells in advanced ovarian cancer

BACKGROUND: At diagnosis, tumor-infiltrating lymphocytes (TILs) are prognostic in epithelial ovarian cancer (EOC). We recently demonstrated that neoadjuvant chemotherapy (NACT) significantly increased stromal TILs. Here, we investigated the impact of NACT on immune subpopulations with a particular f...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Leary, Alexandra, Genestie, Catherine, Blanc-Durand, Félix, Gouy, Sébastien, Dunant, Ariane, Maulard, Amandine, Drusch, Françoise, Cheaib, Bianca, Michels, Judith, Bentivegna, Enrica, LeFormal, Audrey, Mesnage, Soizick, Morice, Philippe, Pautier, Patricia, Khairallah, Aya S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889679/
https://ncbi.nlm.nih.gov/pubmed/32852603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02670-0
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