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A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans

The four-dengue virus (DENV) serotypes infect several hundred million people annually. For the greatest safety and efficacy, tetravalent DENV vaccines are designed to stimulate balanced protective immunity to all four serotypes. However, this has been difficult to achieve. Clinical trials with a lea...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Nivarthi, Usha K., Swanstrom, Jesica, Delacruz, Matthew J., Patel, Bhumi, Durbin, Anna P., Whitehead, Steve S., Kirkpatrick, Beth D., Pierce, Kristen K., Diehl, Sean A., Katzelnick, Leah, Baric, Ralph S., de Silva, Aravinda M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889627/
https://ncbi.nlm.nih.gov/pubmed/33597521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21384-0
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