Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration

Mechanical stimulation plays a crucial part in the development of intervertebral disc degeneration (IDD). Extracellular matrix (ECM) stiffness, which is a crucial mechanical microenvironment of the nucleus pulposus (NP) tissue, contributes to the pathogenesis of IDD. The mechanosensitive ion channel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Wang, Bingjin, Ke, Wencan, Wang, Kun, Li, Gaocai, Ma, Liang, Lu, Saideng, Xiang, Qian, Liao, Zhiwei, Luo, Rongjin, Song, Yu, Hua, Wenbin, Wu, Xinghuo, Zhang, Yukun, Zeng, Xianlin, Yang, Cao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889339/
https://ncbi.nlm.nih.gov/pubmed/33628392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8884922
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados