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Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation – can blood be used as a surrogate for bone?

Difficulty in obtaining bone tissue is an obstacle to studying epigenetics to understand gene–environment interactions, and their role in disease pathogenesis. Blood is an obvious alternative and in this proof of principle study, our aim was to systematically investigate whether blood is a viable su...

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Bibliographische Detailangaben
Veröffentlicht in:Epigenetics
Hauptverfasser: Ebrahimi, Parvaneh, Luthman, Holger, McGuigan, Fiona E, Akesson, Kristina E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889104/
https://ncbi.nlm.nih.gov/pubmed/32692944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1788325
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