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Epigenome-wide cross-tissue correlation of human bone and blood DNA methylation – can blood be used as a surrogate for bone?

Difficulty in obtaining bone tissue is an obstacle to studying epigenetics to understand gene–environment interactions, and their role in disease pathogenesis. Blood is an obvious alternative and in this proof of principle study, our aim was to systematically investigate whether blood is a viable su...

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Detalles Bibliográficos
Publicado en:Epigenetics
Main Authors: Ebrahimi, Parvaneh, Luthman, Holger, McGuigan, Fiona E, Akesson, Kristina E
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889104/
https://ncbi.nlm.nih.gov/pubmed/32692944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1788325
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