Downregulation of PAICS due to loss of chromosome 4q is associated with poor survival in stage III colorectal cancer

Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) encodes an enzyme that catalyzes de novo purine biosynthesis. Although PAICS has been implicated as a potential therapeutic target in several cancers, its clinical and prognostic significance...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Kobayashi, Yusuke, Kumamoto, Kensuke, Okayama, Hirokazu, Matsumoto, Takuro, Nakano, Hiroshi, Saito, Katsuharu, Matsumoto, Yoshiko, Endo, Eisei, Kanke, Yasuyuki, Watanabe, Yohei, Onozawa, Hisashi, Fujita, Shotaro, Sakamoto, Wataru, Saito, Motonobu, Momma, Tomoyuki, Takenoshita, Seiichi, Kono, Koji
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2021
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7888640/
https://ncbi.nlm.nih.gov/pubmed/33596246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0247169
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