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Structure of human BCCIP and implications for binding and modification of partner proteins
BCCIP was isolated based on its interactions with tumor suppressors BRCA2 and p21. Knockdown or knockout of BCCIP causes embryonic lethality in mice. BCCIP deficient cells exhibit impaired cell proliferation and chromosome instability. BCCIP also plays a key role in biogenesis of ribosome 60S subuni...
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| I publikationen: | Protein Sci |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
John Wiley & Sons, Inc.
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7888581/ https://ncbi.nlm.nih.gov/pubmed/33452718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.4026 |
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