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Recruitment of PP1 to the centrosomal scaffold protein CEP192

Centrosomal protein of 192 kDa (CEP192) is a scaffolding protein that recruits the mitotic protein kinases Aurora A and PLK1 to the centrosome. Here we demonstrate that CEP192 also recruits the type one protein phosphatase (PP1) via a highly conserved KHVTF docking motif. The threonine of the KHVTF...

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Detalles Bibliográficos
Publicado en:Biochem Biophys Res Commun
Main Authors: Nasa, Isha, Trinkle-Mulcahy, Laura, Douglas, P., Chaudhuri, Sibapriya, Lees-Miller, S.P., Lee, Kyung S., Moorhead, Greg B.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7888556/
https://ncbi.nlm.nih.gov/pubmed/28188792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.02.004
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