The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions

The dentate gyrus (DG) controls information flow into the hippocampus and is critical for learning, memory, pattern separation, and spatial coding, while DG dysfunction is associated with neuropsychiatric disorders. Despite its importance, the molecular mechanisms regulating DG neural circuit assemb...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Cheng, Jinxuan, Scala, Federico, Blanco, Francisco A., Niu, Sanyong, Firozi, Karen, Keehan, Laura, Mulherkar, Shalaka, Froudarakis, Emmanouil, Li, Lingyong, Duman, Joseph G., Jiang, Xiaolong, Tolias, Kimberley F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7888217/
https://ncbi.nlm.nih.gov/pubmed/33328293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3271-17.2020
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