Dynamic Control of Excitatory Synapse Development by a Rac1 GEF/GAP Regulatory Complex

The small GTPase Rac1 orchestrates actin-dependent remodeling essential for numerous cellular processes including synapse development. While precise spatiotemporal regulation of Rac1 is necessary for its function, little is known about the mechanisms that enable Rac1 activators (GEFs) and inhibitors...

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Autors principals: Um, Kyongmi, Niu, Sanyong, Duman, Joseph G., Cheng, Jinxuan, Tu, Yen-Kuei, Schwechter, Brandon, Liu, Feng, Hiles, Laura, Narayanan, Anjana, Ash, Ryan T., Mulherkar, Shalaka, Alpadi, Kannan, Smirnakis, Stelios M., Tolias, Kimberley F.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111230/
https://ncbi.nlm.nih.gov/pubmed/24960694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.05.011
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