Dynamic Control of Excitatory Synapse Development by a Rac1 GEF/GAP Regulatory Complex

The small GTPase Rac1 orchestrates actin-dependent remodeling essential for numerous cellular processes including synapse development. While precise spatiotemporal regulation of Rac1 is necessary for its function, little is known about the mechanisms that enable Rac1 activators (GEFs) and inhibitors...

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Detalhes bibliográficos
Main Authors: Um, Kyongmi, Niu, Sanyong, Duman, Joseph G., Cheng, Jinxuan, Tu, Yen-Kuei, Schwechter, Brandon, Liu, Feng, Hiles, Laura, Narayanan, Anjana, Ash, Ryan T., Mulherkar, Shalaka, Alpadi, Kannan, Smirnakis, Stelios M., Tolias, Kimberley F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111230/
https://ncbi.nlm.nih.gov/pubmed/24960694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.05.011
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