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Simultaneous Determination of Six Alkaloids in Rat Plasma by SPE-HPLC–MS/MS and Their Pharmacokinetics after Oral Administration of Radix aconiti Preparata Extract
[Image: see text] Simultaneous determination of the content of six alkaloids (aconitine, hypoaconitine, mesaconitine, benzoylaconine, benzoylhypaconine, and benzoylmesaconine) in rat plasma is enabled by HPLC–MS/MS combined with microsolid phase extraction (micro-SPE). To study its pharmacokinetics...
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| Publicado no: | ACS Pharmacol Transl Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2020
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7887741/ https://ncbi.nlm.nih.gov/pubmed/33615166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.0c00133 |
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