Simultaneous Evaluation of the Influence of Panax ginseng on the Pharmacokinetics of Three Diester Alkaloids after Oral Administration of Aconiti Lateralis Radix in Rats Using UHPLC/QQQ-MS/MS

OBJECTIVES: To investigate whether Panax ginseng (P. ginseng) could affect the metabolism of Diester Alkaloids (DAs) derived from Aconiti Lateralis Radix in vivo. METHODS AND RESULTS: 24 male Sprague-Dawley rats were randomized for 7-day treatment with P. ginseng (low, middle, and high), or vehicle....

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Yang, Liang, Wang, Yuguang, Huang, Guangyao, Li, Jian, Zhang, Zhaoyan, Ma, Zengchun, Gao, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304572/
https://ncbi.nlm.nih.gov/pubmed/30622607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/6527549
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