Panax ginseng Inhibits Metabolism of Diester Alkaloids by Downregulating CYP3A4 Enzyme Activity via the Pregnane X Receptor

To investigate the effects of P. ginseng C.A. Mey (P. ginseng) on the metabolism of diester alkaloids and explore the potential mechanism. P. ginseng was administered orally to rats for 7 days, after which liver microsome samples were prepared and then incubated with diester alkaloids. Ultra-high pe...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Yang, Liang, Wang, Yuguang, Xu, Huanhua, Huang, Guangyao, Zhang, Zhaoyan, Ma, Zengchun, Gao, Yue
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463675/
https://ncbi.nlm.nih.gov/pubmed/31057647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3508658
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