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Inhibition Lysosomal Degradation of Clusterin by Protein Kinase D3 Promotes Triple‐Negative Breast Cancer Tumor Growth

Triple negative breast cancer (TNBC), with its lack of targeted therapies, shows the worst mortality rate among all breast cancer subtypes. Clusterin (CLU) is implicated to play important oncogenic roles in cancer via promoting various downstream oncogenic pathways. Here, protein kinase D3 (PRKD3) i...

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Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Liu, Yan, Zhou, Yehui, Ma, Xinxing, Chen, Liming
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7887572/
https://ncbi.nlm.nih.gov/pubmed/33643800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202003205
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