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Mutant p53 as a Regulator and Target of Autophagy

One of the most notoriously altered genes in human cancer is the tumor-suppressor TP53, which is mutated with high frequency in more cancers than any other tumor suppressor gene. Beyond the loss of wild-type p53 functions, mutations in the TP53 gene often lead to the expression of full-length protei...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Shi, Yong, Norberg, Erik, Vakifahmetoglu-Norberg, Helin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886977/
https://ncbi.nlm.nih.gov/pubmed/33614491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.607149
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