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Molecular basis and therapeutic implications of CD40/CD40L immune checkpoint

The CD40 receptor and its ligand CD40L is one of the most critical molecular pairs of the stimulatory immune checkpoints. Both CD40 and CD40 L have a membrane form and a soluble form generated by proteolytic cleavage or alternative splicing. CD40 and CD40L are widely expressed in various types of ce...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmacol Ther
Egile Nagusiak: Tang, TingTing, Cheng, Xiang, Truong, Billy, Sun, LiZhe, Yang, XiaoFeng, Wang, Hong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886970/
https://ncbi.nlm.nih.gov/pubmed/33091428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2020.107709
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