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Molecular basis and therapeutic implications of CD40/CD40L immune checkpoint
The CD40 receptor and its ligand CD40L is one of the most critical molecular pairs of the stimulatory immune checkpoints. Both CD40 and CD40 L have a membrane form and a soluble form generated by proteolytic cleavage or alternative splicing. CD40 and CD40L are widely expressed in various types of ce...
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| Publicado no: | Pharmacol Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7886970/ https://ncbi.nlm.nih.gov/pubmed/33091428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2020.107709 |
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