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The Protective HIV-1 Envelope gp41 Antigen P1 Acts as a Mucosal Adjuvant Stimulating the Innate Immunity

Mucosal nasal vaccine development, although ideal to protect from pathogens invading mucosally, is limited by the lack of specific adjuvant. We recently used P1, a conserved region of HIV-1 gp41-envelope glycoprotein, as efficient antigen in a prophylactic HIV-1 mucosal vaccine applied nasally. Here...

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Pubblicato in:Front Immunol
Autori principali: Xu, Lin, Tudor, Daniela, Bomsel, Morgane
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886812/
https://ncbi.nlm.nih.gov/pubmed/33613520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.599278
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