Imbalanced turnover of collagen type III is associated with disease progression and mortality in high-risk chronic kidney disease patients

BACKGROUND: Tubulointerstitial fibrosis is a major pathological feature in chronic kidney disease (CKD) and collagen type III (COL3) is a major component of the renal fibrotic scar. We hypothesized that a dysregulated turnover of COL3 is an important determinant of CKD progression. We assessed the r...

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Veröffentlicht in:Clin Kidney J
Hauptverfasser: Genovese, Federica, Rasmussen, Daniel Guldager Kring, Karsdal, Morten A, Jesky, Mark, Ferro, Charles, Fenton, Anthony, Cockwell, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886548/
https://ncbi.nlm.nih.gov/pubmed/33623684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfz174
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