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Urinary endotrophin predicts disease progression in patients with chronic kidney disease

Renal fibrosis is the central pathogenic process in progression of chronic kidney disease (CKD). Collagen type VI (COL VI) is upregulated in renal fibrosis. Endotrophin is released from COL VI and promotes pleiotropic pro-fibrotic effects. Kidney disease severity varies considerably and accurate inf...

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Foilsithe in:Sci Rep
Main Authors: Rasmussen, Daniel Guldager Kring, Fenton, Anthony, Jesky, Mark, Ferro, Charles, Boor, Peter, Tepel, Martin, Karsdal, Morten Asser, Genovese, Federica, Cockwell, Paul
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725589/
https://ncbi.nlm.nih.gov/pubmed/29229941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17470-3
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