Urinary endotrophin predicts disease progression in patients with chronic kidney disease

Renal fibrosis is the central pathogenic process in progression of chronic kidney disease (CKD). Collagen type VI (COL VI) is upregulated in renal fibrosis. Endotrophin is released from COL VI and promotes pleiotropic pro-fibrotic effects. Kidney disease severity varies considerably and accurate inf...

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Published in:Sci Rep
Main Authors: Rasmussen, Daniel Guldager Kring, Fenton, Anthony, Jesky, Mark, Ferro, Charles, Boor, Peter, Tepel, Martin, Karsdal, Morten Asser, Genovese, Federica, Cockwell, Paul
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5725589/
https://ncbi.nlm.nih.gov/pubmed/29229941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17470-3
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