Oligodendrocyte-derived extracellular vesicles as antigen-specific therapy for autoimmune neuroinflammation in mice

Autoimmune diseases such as multiple sclerosis (MS) develop because of failed peripheral immune tolerance for a specific self-antigen (Ag). Numerous approaches for Ag-specific suppression of autoimmune neuroinflammation have been proven effective in experimental autoimmune encephalomyelitis (EAE), a...

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Gepubliceerd in:Sci Transl Med
Hoofdauteurs: Casella, Giacomo, Rasouli, Javad, Boehm, Alexandra, Zhang, Weifeng, Xiao, Dan, Ishikawa, Larissa Lumi Watanabe, Thome, Rodolfo, Li, Xing, Hwang, Daniel, Porazzi, Patrizia, Molugu, Sudheer, Tang, Hsin-Yao, Zhang, Guang-Xian, Ciric, Bogoljub, Rostami, Abdolmohamad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886371/
https://ncbi.nlm.nih.gov/pubmed/33148622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aba0599
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