Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance

Homing-based gene drives use a germline source of nuclease to copy themselves at specific target sites in a genome and bias their inheritance. Such gene drives can be designed to spread and deliberately suppress populations of malaria mosquitoes by impairing female fertility. However, strong uninten...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Hammond, Andrew, Karlsson, Xenia, Morianou, Ioanna, Kyrou, Kyros, Beaghton, Andrea, Gribble, Matthew, Kranjc, Nace, Galizi, Roberto, Burt, Austin, Crisanti, Andrea, Nolan, Tony
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886172/
https://ncbi.nlm.nih.gov/pubmed/33513149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009321
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