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Immunotherapy efficacy on mismatch repair-deficient colorectal cancer: from bench to bedside

Colorectal cancers (CRCs) with deficient mismatch repair (dMMR) or microsatellite instability-high (MSI-H) often have sustained responses to immune checkpoint inhibitors (ICIs) including selective monoclonal antibodies against Program Death 1 (PD-1), Programmed Death Ligand 1(PD-L1), and cytotoxic T...

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Bibliographische Detailangaben
Veröffentlicht in:Biochim Biophys Acta Rev Cancer
Hauptverfasser: Lizardo, Darleny Y, Kuang, Chaoyuan, Hao, Suisui, Yu, Jian, Huang, Yi, Zhang, Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886024/
https://ncbi.nlm.nih.gov/pubmed/33035640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2020.188447
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