Survival of patients with deficient mismatch repair metastatic colorectal cancer in the pre-immunotherapy era

BACKGROUND: Metastatic colorectal cancer patients with deficient mismatch repair (dMMR mCRC) benefit from immunotherapy. Interpretation of the single-arm immunotherapy trials is complicated by insignificant survival data during systemic non-immunotherapy. We present survival data on a large, compreh...

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Publicado no:Br J Cancer
Main Authors: Wensink, G. Emerens, Elferink, Marloes A. G., May, Anne M., Mol, Linda, Hamers, Patricia A. H., Bakker, Sandra D., Creemers, Geert-Jan, de Groot, Jan Willem B., de Klerk, Gerty J., Haberkorn, Brigitte C. M., Haringhuizen, Annebeth W., Hoekstra, Ronald, Hunting, J. Cornelis B., Kerver, Emile D., Mathijssen-van Stein, Danielle, Polée, Marco B., Pruijt, Johannes F. M., Quarles van Ufford-Mannesse, Patricia, Radema, Sandra, Rietbroek, Ronald C., Simkens, Lieke H. J., Tanis, Bea C., ten Bokkel Huinink, Daan, Tjin-A-Ton, Manuel L. R., Tromp-van Driel, Cathrien S., Troost, Monique M., van de Wouw, Agnes J., van den Berkmortel, Franchette W. P. J., van der Pas, Anke J. M., van der Velden, Ankie M. T., van Dijk, Marjan A., van Dodewaard-de Jong, Joyce M., van Druten, Edith B., van Voorthuizen, Theo, Jan Veldhuis, Gerrit, Verheul, Henk M. W., Vestjens, Hanneke J. H. M. J., Vincent, Jeroen, Kranenburg, Onno W., Punt, Cornelis J. A., Vink, Geraldine R., Roodhart, Jeanine M. L., Koopman, Miriam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852682/
https://ncbi.nlm.nih.gov/pubmed/33046804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01076-0
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