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The Methionase Chain Reaction: An enzyme-based autocatalytic amplification system for the detection of thiols()

We present an autocatalytic system for the detection and amplification of thiols termed the methionase chain reaction (MCR). MCR is based on the reversible modification of the thiol producing enzyme methionine gamma-lyase (MGL). MCR was able to amplify the concentration of thiols by a factor of 560...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chem Commun (Camb)
Hauptverfasser: Adams, Jeremy David, Røise, Joachim Justad, Lee, David Sam, Murthy, Niren
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886004/
https://ncbi.nlm.nih.gov/pubmed/32065188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc09136j
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