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CD19 CAR-T expressing PD-1/CD28 chimeric switch receptor as a salvage therapy for DLBCL patients treated with different CD19-directed CAR T-cell therapies

CD19-targeted chimeric antigen receptor T (CAR T) cell therapy is a promising option to treat relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL). However, the majority of CAR T-treated patients will eventually progress and require salvage treatment, for which there is no current standard....

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Liang, Yun, Liu, Hui, Lu, Zheming, Lei, Wen, Zhang, Chaoting, Li, Ping, Liang, Aibin, Young, Ken H., Qian, Wenbin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885572/
https://ncbi.nlm.nih.gov/pubmed/33593414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01044-y
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