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Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma
BACKGROUND: Activating Gα(q) signalling mutations are considered an early event in the development of uveal melanoma. Whereas most tumours harbour a mutation in GNAQ or GNA11, CYSLTR2 (encoding G-protein coupled receptor CysLT(2)R) forms a rare alternative. The role of wild-type CysLT(2)R in uveal m...
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| Yayımlandı: | BMC Cancer |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7885466/ https://ncbi.nlm.nih.gov/pubmed/33588787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-07865-x |
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