GABAergic neuron-specific whole-brain transduction by AAV-PHP.B incorporated with a new GAD65 promoter

GABAergic interneurons play a critical role in tuning neural networks in the central nervous system, and their defects are associated with neuropsychiatric disorders. Currently, the mDlx enhancer is solely used for adeno-associated virus (AAV) vector-mediated transgene delivery into cortical interne...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Brain
Auteurs principaux: Hoshino, Chiaki, Konno, Ayumu, Hosoi, Nobutake, Kaneko, Ryosuke, Mukai, Ryo, Nakai, Junichi, Hirai, Hirokazu
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885384/
https://ncbi.nlm.nih.gov/pubmed/33588899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00746-1
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