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Engineering mono- and multi-valent inhibitors on a modular scaffold
Here we exploit the simple, ultra-stable, modular architecture of consensus-designed tetratricopeptide repeat proteins (CTPRs) to create a platform capable of displaying both single as well as multiple functions and with diverse programmable geometrical arrangements by grafting non-helical short lin...
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| Publié dans: | Chem Sci |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Royal Society of Chemistry
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7885266/ https://ncbi.nlm.nih.gov/pubmed/33623657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03175e |
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