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Decoupling a tandem-repeat protein: Impact of multiple loop insertions on a modular scaffold
The simple topology and modular architecture of tandem-repeat proteins such as tetratricopeptide repeats (TPRs) and ankyrin repeats makes them straightforward to dissect and redesign. Repeat-protein stability can be manipulated in a predictable way using site-specific mutations. Here we explore a di...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6817815/ https://ncbi.nlm.nih.gov/pubmed/31659184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49905-4 |
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