Nrf2 Regulates Granuloma Formation and Macrophage Activation during Mycobacterium avium Infection via Mediating Nramp1 and HO-1 Expressions

Nrf2 is a redox-sensitive transcription factor that is thought to be important in protection against intracellular pathogens. To determine the protective role of Nrf2 in the host defense against Mycobacterium avium complex (MAC), both wild-type and Nrf2-deficient mice were intranasally infected with...

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發表在:mBio
Main Authors: Nakajima, Masayuki, Matsuyama, Masashi, Kawaguchi, Mio, Kiwamoto, Takumi, Matsuno, Yosuke, Morishima, Yuko, Yoshida, Kazufumi, Sherpa, Mingma, Yazaki, Kai, Osawa, Hajime, Muratani, Masafumi, Ishii, Yukio, Hizawa, Nobuyuki
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2021
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885113/
https://ncbi.nlm.nih.gov/pubmed/33563837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01947-20
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