microRNA-183–5p induces cell density-dependent apoptosis through the regulation of Presenilin 2

Cells undergo apoptosis under dense culture condition to maintain homeostasis. Impaired apoptosis may contribute to the excessive accumulation of pathogenetic cells in such diseases as cancer and organ fibrosis. Elucidating the molecular mechanisms regulating cell density-dependent apoptosis may pro...

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Главные авторы:	Yuki Yabuuchi, Yosuke Matsuno, Kai Yazaki, Wei Zhen Ting, Kengo Nishino, Sosuke Matsumura, Kenya Kuramoto, Kazufumi Yoshida, Masashi Matsuyama, Takumi Kiwamoto, Yuko Morishima, Nobuyuki Hizawa
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2025-06-01
Серии:	European Journal of Cell Biology
Предметы:	Akt B cell lymphoma-2 Notch signaling pathway microRNA 183–5p Phosphatidylinositol-3 kinase Presenilin 2
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S0171933525000196
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