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Resistance to a Nucleoside Analog Antiviral Drug from More Rapid Extension of Drug-Containing Primers

Nucleoside analogs are mainstays of antiviral therapy. Although resistance to these drugs hinders their use, understanding resistance can illuminate mechanisms of the drugs and their targets. Certain nucleoside analogs, such as ganciclovir (GCV), a leading therapy for human cytomegalovirus (HCMV), c...

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Publicat a:mBio
Autors principals: Chen, Han, Lawler, Jessica L., Filman, David J., Hogle, James M., Coen, Donald M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885103/
https://ncbi.nlm.nih.gov/pubmed/33563814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03492-20
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