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Resistance to a Nucleoside Analog Antiviral Drug from More Rapid Extension of Drug-Containing Primers

Nucleoside analogs are mainstays of antiviral therapy. Although resistance to these drugs hinders their use, understanding resistance can illuminate mechanisms of the drugs and their targets. Certain nucleoside analogs, such as ganciclovir (GCV), a leading therapy for human cytomegalovirus (HCMV), c...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Chen, Han, Lawler, Jessica L., Filman, David J., Hogle, James M., Coen, Donald M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885103/
https://ncbi.nlm.nih.gov/pubmed/33563814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03492-20
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