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Resistance to a Nucleoside Analog Antiviral Drug from More Rapid Extension of Drug-Containing Primers

Nucleoside analogs are mainstays of antiviral therapy. Although resistance to these drugs hinders their use, understanding resistance can illuminate mechanisms of the drugs and their targets. Certain nucleoside analogs, such as ganciclovir (GCV), a leading therapy for human cytomegalovirus (HCMV), c...

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Publicado en:mBio
Main Authors: Chen, Han, Lawler, Jessica L., Filman, David J., Hogle, James M., Coen, Donald M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885103/
https://ncbi.nlm.nih.gov/pubmed/33563814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03492-20
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