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Topoisomerase 2β Induces DNA Breaks To Regulate Human Papillomavirus Replication

Topoisomerases regulate higher-order chromatin structures through the transient breaking and religating of one or both strands of the phosphodiester backbone of duplex DNA. TOP2β is a type II topoisomerase that induces double-strand DNA breaks at topologically associated domains (TADS) to relieve to...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Kaminski, Paul, Hong, Shiyuan, Kono, Takeyuki, Hoover, Paul, Laimins, Laimonis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885102/
https://ncbi.nlm.nih.gov/pubmed/33563836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00005-21
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