Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis

Pulmonary alveolar proteinosis (PAP) is a devastating lung disease caused by abnormal surfactant homeostasis, with a prevalence of 6–7 cases per million population worldwide. While mutations causing hereditary PAP have been reported, the genetic basis contributing to autoimmune PAP (aPAP) has not be...

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Publicado no:Nat Commun
Main Authors: Sakaue, Saori, Yamaguchi, Etsuro, Inoue, Yoshikazu, Takahashi, Meiko, Hirata, Jun, Suzuki, Ken, Ito, Satoru, Arai, Toru, Hirose, Masaki, Tanino, Yoshinori, Nikaido, Takefumi, Ichiwata, Toshio, Ohkouchi, Shinya, Hirano, Taizou, Takada, Toshinori, Miyawaki, Satoru, Dofuku, Shogo, Maeda, Yuichi, Nii, Takuro, Kishikawa, Toshihiro, Ogawa, Kotaro, Masuda, Tatsuo, Yamamoto, Kenichi, Sonehara, Kyuto, Tazawa, Ryushi, Morimoto, Konosuke, Takaki, Masahiro, Konno, Satoshi, Suzuki, Masaru, Tomii, Keisuke, Nakagawa, Atsushi, Handa, Tomohiro, Tanizawa, Kiminobu, Ishii, Haruyuki, Ishida, Manabu, Kato, Toshiyuki, Takeda, Naoya, Yokomura, Koshi, Matsui, Takashi, Watanabe, Masaki, Inoue, Hiromasa, Imaizumi, Kazuyoshi, Goto, Yasuhiro, Kida, Hiroshi, Fujisawa, Tomoyuki, Suda, Takafumi, Yamada, Takashi, Satake, Yasuomi, Ibata, Hidenori, Hizawa, Nobuyuki, Mochizuki, Hideki, Kumanogoh, Atsushi, Matsuda, Fumihiko, Nakata, Koh, Hirota, Tomomitsu, Tamari, Mayumi, Okada, Yukinori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884840/
https://ncbi.nlm.nih.gov/pubmed/33589587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21011-y
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