cGAMP/Saponin Adjuvant Combination Improves Protective Response to Influenza Vaccination by Microneedle Patch in an Aged Mouse Model

Current strategies for improving protective response to influenza vaccines during immunosenescence do not adequately protect individuals over 65 years of age. Here, we used an aged mouse model to investigate the potential of co-delivery of influenza vaccine with the recently identified combination o...

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Publicat a:Front Immunol
Autors principals: Vassilieva, Elena V., Li, Song, Korniychuk, Heorhiy, Taylor, Dahnide M., Wang, Shelly, Prausnitz, Mark R., Compans, Richard W.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884748/
https://ncbi.nlm.nih.gov/pubmed/33603732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.583251
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