A balance score between immune stimulatory and suppressive microenvironments identifies mediators of tumour immunity and predicts pan-cancer survival

BACKGROUND: The balance between immune-stimulatory and immune-suppressive mechanisms in the tumour microenvironment is associated with tumour rejection and can predict the efficacy of immune checkpoint-inhibition therapies. METHODS: We consider the observed differences between the transcriptional pr...

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Udgivet i:Br J Cancer
Main Authors: Turan, Tolga, Kongpachith, Sarah, Halliwill, Kyle, Roelands, Jessica, Hendrickx, Wouter, Marincola, Francesco M., Hudson, Thomas J., Jacob, Howard J., Bedognetti, Davide, Samayoa, Josue, Ceccarelli, Michele
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884411/
https://ncbi.nlm.nih.gov/pubmed/33139798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01145-4
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