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High-throughput behavioral screen in C. elegans reveals Parkinson’s disease drug candidates
We recently linked branched-chain amino acid transferase 1 (BCAT1) dysfunction with the movement disorder Parkinson’s disease (PD), and found that RNAi-mediated knockdown of neuronal bcat-1 in C. elegans causes abnormal spasm-like ‘curling’ behavior with age. Here we report the development of a mach...
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| 出版年: | Commun Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7884385/ https://ncbi.nlm.nih.gov/pubmed/33589689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01731-z |
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