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An integrative tissue-network approach to identify and test human disease genes

Effective discovery of causal disease genes must overcome the statistical challenges of quantitative genetics studies and the practical limitations of human biology experiments. Here we developed diseaseQUEST, an integrative approach that combines data from human genome-wide disease studies with in...

詳細記述

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書誌詳細
出版年:Nat Biotechnol
主要な著者: Yao, Victoria, Kaletsky, Rachel, Keyes, William, Mor, Danielle E, Wong, Aaron K, Sohrabi, Salman, Murphy, Coleen T, Troyanskaya, Olga G
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021177/
https://ncbi.nlm.nih.gov/pubmed/30346941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4246
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