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An integrative tissue-network approach to identify and test human disease genes

Effective discovery of causal disease genes must overcome the statistical challenges of quantitative genetics studies and the practical limitations of human biology experiments. Here we developed diseaseQUEST, an integrative approach that combines data from human genome-wide disease studies with in...

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Podrobná bibliografie
Vydáno v:Nat Biotechnol
Hlavní autoři: Yao, Victoria, Kaletsky, Rachel, Keyes, William, Mor, Danielle E, Wong, Aaron K, Sohrabi, Salman, Murphy, Coleen T, Troyanskaya, Olga G
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021177/
https://ncbi.nlm.nih.gov/pubmed/30346941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4246
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