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An integrative tissue-network approach to identify and test human disease genes

Effective discovery of causal disease genes must overcome the statistical challenges of quantitative genetics studies and the practical limitations of human biology experiments. Here we developed diseaseQUEST, an integrative approach that combines data from human genome-wide disease studies with in...

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Bibliografische gegevens
Gepubliceerd in:Nat Biotechnol
Hoofdauteurs: Yao, Victoria, Kaletsky, Rachel, Keyes, William, Mor, Danielle E, Wong, Aaron K, Sohrabi, Salman, Murphy, Coleen T, Troyanskaya, Olga G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021177/
https://ncbi.nlm.nih.gov/pubmed/30346941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.4246
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