Role of MDA5 in regulating CXCL10 expression induced by TLR3 signaling in human rheumatoid fibroblast-like synoviocytes

C-X-C motif chemokine 10 (CXCL10) is an inflammatory chemokine and a key molecule in the pathogenesis of rheumatoid arthritis (RA). Melanoma differentiation-associated gene 5 (MDA5) is an RNA helicase that plays a role in innate immune and inflammatory reactions. The details of the regulatory mechan...

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Detalles Bibliográficos
Publicado en:Mol Biol Rep
Main Authors: Saruga, Tatsuro, Imaizumi, Tadaatsu, Kawaguchi, Shogo, Seya, Kazuhiko, Matsumiya, Tomoh, Sasaki, Eiji, Sasaki, Norihiro, Uesato, Ryoko, Ishibashi, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2021
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7884359/
https://ncbi.nlm.nih.gov/pubmed/33387195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-020-06069-z
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