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How are STAT1 and cholesterol metabolism associated in antiviral responses?

Sterol metabolites are known to be associated with immune responses. 25-Hydroxycholesterol (25HC) is a cholesterol metabolite that is produced by macrophages. The production of 25HC was reported to be TLR-dependent, indicating the involvement of 25HC in innate immunity. Now Blanc et al. show that ma...

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Bibliographic Details
Main Authors: Matsumiya, Tomoh, Imaizumi, Tadaatsu
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772106/
https://ncbi.nlm.nih.gov/pubmed/24069554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/jkst.24189
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